The Waters Xevo TQ Asbolute with Acquity I-Class Premier is our newest high performance instrument and used for high sensitivity targeted quantitative analysis of metabolites, lipids, peptides or other small molecule compounds. The Acquity I-Class Premier system consists of a quaternary solvent manager (BSM), column manager (CM; four UPLC 50 mm columns plus 1 custom user defined column position) and  a  sample manger (FTN SM) and sample organizer (SO) (12 plate capacity: various configurations for 48-vials, 96-well or 384 well plates). The Acquity UPLC Premier LC system features Waters proprietary flow path/column coating to eliminate passivity losses for challenging analytes (P or S compounds) giving improved peak shapes and sensitivity. The TQ Absolute can be opreated with a variety of input sources and ionization modes (ESI+ or ESI- mode; APCI+ or - is also available).

 

Access: walk-up open access (reserve time via on-line calendar)

Columns: column manager with C4, C18, Fusion-C18 or HILIC as standard or user selected custom (PFP, amide, amino etc.)

Mode: ESI+, ESI- (or APCi+, APCI-)

Solvent: A1 (0.2 % acetic acid, 2 % acetonitrile in water), B1 (acetonitrile + 0.2 % acetic acid; or A2B2 user defined

M/z: Parent/daughter ions, CV, CE defined by user or trained by QuantOptimize

Analyzer: triplequadrupole

Autosampler: 12 plate sample organizer (diverse vial and plate configurations)