The Waters Synapt G2 is a high resolution TOF/TOF instrument suitable for analysis of complex samples (peptides/proteins/metabolomics). An advanced Waters Acquity iClass UPLC and column manager provide versatile column chemistry and separations capabilities. The Synapt G2 also has an in-line ion mobility (IM) drift tube for orthogonal separation of isobaric species by molecular shape.

A separate hydrogen-deuteriume exchange (HDX) Acquity LC stack provides capabilities for protein-protein interaction domain mapping and enzyme reaction kinetic studies.

 

Access: Walk-up Open Access

Column: Acquity CM for UPLC C4, C18, HILIC and various other column chemistries

Solvents: 0.1 % FA, water, acetonitrile, methanol, or custom buffers

Analyzer: TOF/TOF and IMS

Autosampler: 2 x 48-well vial plates

Software: MassLynx 4.1 (w; driftscope for IMS)